Oncology

ONC: MNT Interventions for Cancer Patients (2024-25)

Intervention
In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on nutrition status?
- Conclusion
  Dietitian interventions may improve nutrition status in adults with cancer, particularly head and neck or GI cancer, compared to no intervention or usual care.
- Grade: Low (C)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on nutrition status?
- Search Plan and Results: ONC: Medical Nutrition Therapy for Cancer Patients (2025)
In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on quality of life?
- Conclusion
  In adults with cancer, dietitian interventions may improve or have no effect on quality of life compared to no intervention or usual care, but evidence is uncertain.
- Grade: Very Low (D)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on quality of life?
- Search Plan and Results: ONC: Medical Nutrition Therapy for Cancer Patients (2025)
In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on hospital length of stay?
- Conclusion
  Dietitian interventions may decrease length of stay compared to no intervention or usual care in adults with gastrointestinal cancer, but the evidence is uncertain.
- Grade: Very Low (D)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on hospital length of stay?
- Search Plan and Results: ONC: Medical Nutrition Therapy for Cancer Patients (2025)
In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on mortality?
- Conclusion
  Dietitian interventions may result in little to no difference in mortality for adults with cancer compared to no intervention or usual care.
- Grade: Low (C)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on mortality?
- Search Plan and Results: ONC: Medical Nutrition Therapy for Cancer Patients (2025)
In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on weight?
- Conclusion
  Evidence suggests dietitian interventions may improve body weight outcomes in adults with cancer, particularly with head and neck or gastrointestinal cancer, or may have no effect on body weight compared to no intervention or usual care.
- Grade: Very Low (D)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on weight?
- Search Plan and Results: ONC: Medical Nutrition Therapy for Cancer Patients (2025)
In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on protein intake?
- Conclusion
  Dietitian interventions may increase protein intake in adults with cancer compared to no intervention or usual care.
- Grade: Low (C)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on protein intake?
- Search Plan and Results: ONC: Medical Nutrition Therapy for Cancer Patients (2025)
In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on energy intake?
- Conclusion
  Dietitian interventions may improve energy intake in adults with cancer compared to no intervention or usual care.
- Grade: Low (C)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with cancer, what is the impact of nutrition interventions provided by dietitians, compared to no intervention or usual care, on energy intake?
- Search Plan and Results: ONC: Medical Nutrition Therapy for Cancer Patients (2025)