Recommendations Summary
T1DM: Nutrition Screening (2024)
Click here to see the explanation of recommendation ratings (Strong, Fair, Weak, Consensus, Insufficient Evidence) and labels (Imperative or Conditional). To see more detail on the evidence from which the following recommendations were drawn, use the hyperlinks in the Supporting Evidence Section below.
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Recommendation(s)
T1DM: Vitamin D Deficiency Screening
In children and adolescents, we suggest screening for vitamin D deficiency at stage I type 1 diabetes (>=2 type 1 diabetes associated islet autoantibodies) or first onset of type 1 diabetes symptoms.
Rating: Consensus
ConditionalT1DM: Screening for Associated Factors
It is reasonable that health care professionals screen for disordered eating behaviors, food insecurity, housing stability/homelessness, health literacy, financial barriers, and social/community support and apply that information to treatment decisions.
Rating: Consensus
Conditional-
Risks/Harms of Implementing This Recommendation
No harms associated with the implementation of this recommendation. No obvious harms or risks associated with screening individuals for risk of eating disorders, vitamin D status or food insecurity issues. No significant cost may be associated with implementing this recommendation. Two recognized costs are the time and expense that may be required to train RDNs to perform the screening. However, most of the training materials are available in print or online and dietitians are typically familiar with these resources, or they are readily discoverable.
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Conditions of Application
Providers can follow guidance of their workplace on conducting the screening.
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Potential Costs Associated with Application
Time and cost may be necessary to train RDNs to conduct this screening. Additional costs will vary according to insurance coverage.
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Recommendation Narrative
Evidence also indicates that vitamin D deficiency is prevalent among all youth in the U.S., including those with T1DM. In children and adolescents (6-19 years old) living with T1DM, vitamin D insufficiency (defined as serum 25-hydroxyvitamin D [25(OH)D] concentrations of 30 - 50 nmol/L or 12 - 20 ng/mL) and/or deficiency (defined as serum 25-hydroxyvitamin D [25(OH)D] concentrations of <30 nmol/L or <12 ng/mL) are common, affecting as many as 63% of patients. Vitamin D supplementation repletes vitamin deficiency but given the notably suboptimal glycemic management among children and adolescents with T1DM, understanding the role of vitamin D supplementation on A1C is imperative. Recent evidence states that vitamin D can protect pancreatic beta cells and hence might help with achieving glycemic targets. Hence, screening individuals with T1DM for vitamin D status can be helpful.
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Recommendation Strength Rationale
This recommendation is based on expert panel's Consensus.
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Minority Opinions
None.
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Risks/Harms of Implementing This Recommendation
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Supporting Evidence
The recommendations were created from the evidence analysis on the following questions. To see detail of the evidence analysis, click the blue hyperlinks below (recommendations rated consensus will not have supporting evidence linked).
In children and adolescents (6-19 years old) living with type 1 diabetes, what is the effect of vitamin D supplementation compared to no supplementation on A1C?
In children and adolescents (6-19 years old) living with type 1 diabetes, what is the association between food insecurity / socioeconomic status and glycemic outcomes and adverse events?-
References
Iovane B, Cangelosi A, Bonaccini I, Mastrorilli C, Di Mauro D, Fainardi V, Chiari G, Maltese M, Caffarelli C, Vanelli M. Effectiveness of a tailored medical support to overcome the barriers to education, treatment and good metabolic control in children with type-1 diabetes from ethnic minorities. Acta Bio-Medica : Atenei Parmensis 2018; 88:477-482
Pascual A, Pyle L, Nieto J, Klingensmith G, Gonzalez A. Novel, culturally sensitive, shared medical appointment model for Hispanic pediatric type 1 diabetes patients. Pediatric Diabetes 2019; 20:468-473
Giri D, Pintus D, Burnside G, Ghatak A, Mehta F, Paul P, Senniappan S. Treating vitamin D deficiency in children with type I diabetes could improve their glycaemic control.. BMC Research Notes 2017; 10:465
Nafei L, Ali Kadhim K, Muaffaq Said A, Hameed Ghani S.. Evaluation the Effect of Vitamin D3 on Glycemic Indices on Iraqi Children with Type 1 DM. International Journal of Pharmaceutical Sciences Review and Research 2017; 42:134-143
Panjiyar R, Dayal D, Attri S, Sachdeva N, Sharma R, Bhalla A. Sustained serum 25-hydroxyvitamin D concentrations for one year with cholecalciferol supplementation improves glycaemic control and slows the decline of residual beta cell function in children with type 1 diabetes. Pediatric Endocrinology, Diabetes, and Metabolism 2018; 2018:111-117
Sharma S, Biswal N, Bethou A, Rajappa M, Kumar S, Vinayagam V. Does Vitamin D Supplementation Improve Glycaemic Control In Children With Type 1 Diabetes Mellitus? - A Randomized Controlled Trial. Journal of Clinical and Diagnostic Research 2017; 11:SC15-SC17
Shih E, Mittelman S, Pitukcheewanont P, Azen C, Monzavi R. Effects of vitamin D repletion on glycemic control and inflammatory cytokines in adolescents with type 1 diabetes. Pediatric Diabetes 2014; 17:36-43
Treiber G, Prietl B, Fröhlich-Reiterer E, Lechner E, Ribitsch A, Fritsch M, Rami-Merhar B, Steigleder-Schweiger C, Graninger W, Borkenstein M, Pieber T. Cholecalciferol supplementation improves suppressive capacity of regulatory T-cells in young patients with new-onset type 1 diabetes mellitus - A randomized clinical trial. Clinical Immunology (Orlando, Fla.) 2015; 161:217-224 -
References not graded in Academy of Nutrition and Dietetics Evidence Analysis Process
- Kumar J, Muntner P, Kaskel FJ, Hailpern SM, Melamed ML. Prevalence and associations of 25-hydroxyvitamin D deficiency in US children: NHANES 2001-2004. Pediatrics. 2009;124(3):e362-370. PMID: 19661054 doi: 10.1542/peds.2009-0051. Epub 2009 Aug 3.
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References