The ideal macronutrient composition for lowering triglycerides in patients with hypertriglyceridemia (TG>150mg/dL) is unclear.  The four studies available are primarily of men, in free-living conditions, consuming self-selected diets with dietary guidance. These small sample size studies varied in duration, TG levels and had discrepant findings.

Similar research has been done in patients with the metabolic syndrome that would offer guidance in this area.

• Grade I means there is Good/Strong evidence supporting the statement;
• Grade II is Fair;
• Grade III is Limited/Weak;
• Grade IV is Expert Opinion Only;
• Grade V is Not Assignable.
• High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
• Moderate (B) means we are moderately confident in the effect estimate;
• Low (C) means our confidence in the effect estimate is limited;
• Very Low (D) means we have very little confidence in the effect estimate.
• Ungraded means a grade is not assignable.